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Administering a single dose greater than 40 mg, or total daily doses greater than 80 mg, to an opioid-naive individual (someone without built-up tolerance) can cause fatal respiratory depression (the slowing or stopping of breathing).
If the tablet is cut, broken, chewed, crushed, or dissolved, the extended-release safety mechanism is destroyed. This causes the entire 80mg dose to be released into the body all at once, which is frequently fatal. OxyContin Fast Facts - Department of Justice buy oxycontin online 80mg
The 80mg tablet is one of the highest doses available and carries extreme risks: Administering a single dose greater than 40 mg,