Dead Space Apr 2026

: This paper in PubMed proposes mathematical models to improve the estimation of functional residual capacity (FRC) by accounting for gas mixing within the dead space, moving beyond traditional lung models.

: This study, available on PMC , highlights that measuring dead space can be a more reliable predictor of Acute Respiratory Distress Syndrome (ARDS) outcomes than oxygenation levels alone. It evaluates various surrogate indices, such as the ventilatory ratio, used in clinical practice when direct measurement is unavailable. Dead Space

(2026): Published in Critical Care , this paper provides a comprehensive overview of dead space from its first description by Christian Bohr in 1891 to modern applications. It discusses the integration of lung imaging and clinical scenarios to assess dead space distribution in critical care settings. : This paper in PubMed proposes mathematical models

: Found in the European Respiratory Journal , this paper explains that elevated physiological dead space is a strong prognostic marker for patients with ARDS and severe heart failure. It identifies ventilation/perfusion ( ) heterogeneity as a primary pathophysiological mechanism. (2026): Published in Critical Care , this paper

: Published in Nature , this research focuses on the impact of dead space on neonatal respiratory support, explaining how anatomical and apparatus dead space (from endotracheal tubes) affects lung-protective ventilation strategies.