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Understanding and Interpreting Serum Protein Electrophoresis

Electrophoresis typically reveals five or six distinct peaks: Key Components Clinical Significance of Changes Main serum protein : The JNMG guide on anomalies provides specific

: Suggests Multiple Myeloma or MGUS. Broad Increase : Chronic infection or autoimmune disease. Key Patterns to Look For Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation

You can find and download detailed clinical guides from these authoritative medical platforms: kidney loss (nephrotic syndrome)

: Download the interpretation guide from FMC Tourcoing for a concise overview of quantitative values.

: The JNMG guide on anomalies provides specific indicators for bone pain or unexplained renal failure.

: Liver disease, kidney loss (nephrotic syndrome), or malnutrition. Increased : Dehydration. Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation. Alpha-2 Haptoglobin, Alpha-2 macroglobulin Increased : Acute phase reaction or nephrotic syndrome. Beta Transferrin, Complement Increased : Iron deficiency or high cholesterol. Two peaks ( ) are visible in capillary tests. Gamma Immunoglobulins (Antibodies)