Upon the introduction of the normal RAR ligand, all-trans-retinoic acid, the chimeric receptor undergoes nuclear translocation. 3. Results: Translocation Tracking
The development of a chimeric receptor that utilizes GR-like translocation properties while retaining RAR ligand specificity provides a robust, visual assay for ligand-receptor interactions. This methodology represents a significant step forward in in vivo monitoring of nuclear receptor signaling. To further refine this paper, please tell me: Hem#265 rar
Are you looking to focus on the of RAR or the technical design of the chimera? Upon the introduction of the normal RAR ligand,
Marine-Derived Bioactive Ingredients in Functional Foods for Aging green fluorescent protein).
The chimera is constructed by fusing the ligand-binding domain of the retinoic acid receptor (RAR) to a reporter sequence that allows tracking (e.g., green fluorescent protein).