: On October 19, Barcelona secured a steady 2-0 victory . While Andrés Iniesta scored a brilliant individual goal, the match was remembered for Plzeň's resilient defense and Lionel Messi's rare night of hitting the woodwork twice rather than the net.
: The return leg on November 1 saw a definitive 4-0 win for the Blaugrana. Lionel Messi silenced any doubts by scoring a hat-trick , which included his 200th career goal for the club. This victory officially secured Barcelona’s place in the knockout stages. The Era of Lewandowski (2022) Pilzno - Barcelona
In the autumn of 2011, the "Golden Era" Barcelona side, managed by Pep Guardiola, faced Plzeň for the first time. : On October 19, Barcelona secured a steady 2-0 victory