Renal Failure -

The leading causes of renal failure globally are and diabetes , which together account for approximately two-thirds of all cases.

Classified into five stages based on the Estimated Glomerular Filtration Rate (eGFR) . A normal eGFR is above 60; levels below this for extended periods indicate progressive damage. renal failure

Chronic Kidney Disease Diagnosis and Management: A Review - PMC The leading causes of renal failure globally are

Clinical Overview: Renal Failure (Kidney Failure) Renal failure occurs when the kidneys lose the ability to sufficiently filter waste products from the blood to sustain life. This condition can manifest as either , characterized by a sudden and often reversible decline in function, or Chronic Kidney Disease (CKD) , a progressive condition that may eventually lead to End-Stage Renal Disease (ESRD) . 1. Classification and Epidemiology Chronic Kidney Disease Diagnosis and Management: A Review

Defined by rapid changes in serum creatinine levels or urine output. It is often caused by sudden trauma, severe infection, or drug toxicity.

Approximately 850 million people worldwide (over 10% of the population) are affected by kidney disease. It is projected to become the fifth leading cause of death globally by 2050. 2. Pathophysiology and Causes