The diagnostic team treats Donny, a reckless police detective convinced he is genetically "doomed" to die of sudden heart failure at age 40, just like his father, grandfather, and great-grandfather. Secondary Plots:

To help House regain his medical license, Cuddy falsifies his required "rounds" paperwork, noting it is easier than forcing him to actually teach students.

Dr. Robert Chase struggles with debilitating guilt and panic attacks after intentionally causing the death of the brutal dictator President Dibala in a previous episode. Medical Case & Diagnosis

The team considers Wilson's disease and hereditary sensory autonomic neuropathy type 1.

House realizes Donny (and his son) has an intracranial berry aneurysm in the brain stem. This "self-destruct button" was growing and occasionally sending faulty signals to the heart, mimicking sudden failure. Both Donny and his long-lost son undergo successful surgery to repair the aneurysms. Character Developments